Biology GPU
The biology resolution runtime for AI
Enabling AI models to experimentally chat with cells through
Visual Biology Computing

We’ve built the experimental modality that enables AI models to reason in causal human biology Pathways seen in action
in space and time
computable for AI



LLM
Multimodal Disease Models
Chat with Cells
Experimental Reasoning Loop
BioGPU
Visual Biology Model Runtime
Multiple cell types across diseases, conditions and perturbations

Biology GPU

The biology resolution runtime for AI

Large-scale experimental infrastructure: Executes AI and omics-derived hypothesis directly in cells, across different disease-relevant cellular systems

Visual computing as a new biological modality: Observe pathway activity and target effects across millions of cellular images, interpreted by a model trained on 2B+ pathway images across ~140 cell types and 25 diseases

Parallel experimental execution: Resolve disease and target biology at scale, rather than one target at a time

BioGPU agent: Enables scientists or LLMs to design experiments, run visual compute, and iteratively test hypotheses against observed pathway activity

Visual Biology Trained Models



Large Visual Computing Model

Generated from 25 disease models trained in real projects with Pharma
Total: 2B+ process visualizations

Visual mRNA Biology Model

Domain specific model that visualizes mRNA biology regulatory mechanisms



BioGPU Agent

Enables LLMs to test biological hypothesis at scale inside cells

See how ChatGPT becomes an autonomous drug discovery engine and resolves causal biology in ALS by iterating in an experimental loop with the Biology GPU





The missing experimental modality AI needs to resolve causal biology across pathways and processes in parallel

Under perturbation, cells activate many pathways at once.

BioGPU makes the full biological consequences of perturbation visible early enough to change decisions.

Visual Computing
inside cells
Biological Processes and Pathways
Partner
AI Disease
Model
Visual Biology
Causal AI
Disease Model
Genomics
Transcriptomics
Proteomics
Pathology
Cellular morphology


What AI can do with the Biology GPU

Disease Signature & Target ID
Discover pathway signatures - compare cellular systems
Discover novel targets that modulate pathway signatures
Target Validation
Understand a target’s biological function
Compare and rank targets by pathway modulation
Hit Identification
Discover compounds with pathway selectivity
Compare clusters for their biological activity - de-risk programs early
Hit To Lead
Elucidate compound’s MOAs
Optimize activity on core pathways
Lead Optimization
Optimize chemistry in a visual biology loop - optimize pathway activity
Predict off-target effects
Preclinical Development
Visual computing toxicity panels
Compare biology across human and animal models

+ Additional use cases in mRNA biology with a specialized mRNA neural network






Resolving disease and target biology

1
Hypothesis

Hundreds of disease hypothesis generated computationally

2
BioGPU

See and compute on pathways inside real biology

3
Casual targets

Targets ranked by cellular activity, drivers separated from passengers

The Team Behind the Biology GPU

Expertise:
mRNA biology
Software
A.I.
Computational Biology
Chemistry
Operations
Imaging

mRNA biology Operations Imaging Iris Alroy PhD., Co-founder & CSO

Software A.I. Ivan Khodyrev PhD., Director, Software Development

mRNA biology Imaging Shaul Barth PhD., Principal Scientist, Assay development & screen Team Lead

mRNA biology Hanoch Tempelhof PhD., Principal Scientist, Target & Pathway exploration Team Lead

mRNA biology Amihai Karniel PhD., Principal Scientist, R&D Quality and Operations Lead

Operations Dana Radha MBA, Head of HR

mRNA biology Alik Demishtein PhD., Principal Scientist, Drug Discovery Team Lead

mRNA biology Software Operations Pascal Brandys Board member

mRNA biology Ephrem Kassa PhD., Principal Scientist, MOA & Target ID Team Lead

mRNA biology Keren Kipnis PhD., Senior Research Scientist, Screen-Unit Manager

Software Operations Fred Voccola Board member

mRNA biology Jasmine Khier PhD., Product Integration Specialist, Senior Scientist

mRNA biology Ofer Bihari PhD., Senior Research Scientist

mRNA biology Sari Trangle PhD., Senior Research Scientist

mRNA biology Ben Bar-Sadeh PhD., Senior Research Scientist

mRNA biology Irit Reichenstein PhD., Senior Research Scientist

mRNA biology Artem Tverskoi PhD., Senior Research Scientist

mRNA biology Adi Amar-Schwartz PhD., Research Scientist

Software Operations Miki Shvo CISO & AWS Admin

mRNA biology Tamar Frankovits PhD., Research Scientist

Chemistry Luba Ischakov Simhaev PhD., Senior Computational Chemist

Chemistry Shuyu Chu PhD., Associate Principal Scientist, Medicinal Chemist

A.I. Chemistry Eitan Margulis PhD., Computational Chemist

Chemistry Andrew Brown PhD., Associate Principal Scientist, Medicinal Chemist

mRNA biology Alon Parsai M.Sc., Senior Research Associate

mRNA biology Racheli Rimmer M.Sc., Senior Research Associate

mRNA biology Ziv Landau M.Sc., Laboratory Supervisor

mRNA biology Linoy Vaturi B.Sc., Senior Research Associate

mRNA biology Ana Miriam Salama M.Sc., Senior Research Associate

mRNA biology Naama Slonim M.Sc., Senior Research Associate

mRNA biology Alisa Lysak B.Sc., Research Associate

Operations Ronit Cohen Financial Operations Manager

mRNA biology Dana Kadosh-Kariti M.Sc., Senior Research Associate

mRNA biology Yifat Weiss M.Sc., Senior Research Associate

mRNA biology Claudia Roussay Maggi M.Sc., Research Associate

Software Nir Katz Software QA Manager

Operations Linda Murikkattu M.Sc., Junior Business Development Associate

Software Mikhail Usik M.Sc., Senior DevOps Engineer

Software Aleksei Mushegov Senior Frontend Developer

Computational Biology Odelia Goldberg-Nakar PhD., Senior Research Data Analyst

A.I. Imaging Lion Ben Nedava M.Sc., Image Analysis Scientist

Computational Biology Luis Alejandro de Haro PhD., Bioinformatician

Software Gilad Livne Senior Backend Developer

A.I. Imaging Nitsan Elmalam M.Sc., AI Researcher

A.I. Imaging Yael Elkin M.Sc., AI Data Scientist

Computational Biology Shaked Bergman PhD., Lead Computational Biologist

Software Tiferet Gan B.Sc., QA Engineer

Software Evelyn Popok B.Sc., Backend Developer

Software Tamir Oulu UI/UX Developer

Operations Stav Yohanan BA, Office Manager

Software Anton Akinin B.Sc., Backend Developer

Operations Catherine Sorromero BA, Executive Assistant



Get started with your Biology GPU

[email protected]